Issue Details
THE EFFECTIVENESS Of SILVER NANOPARTICLES AS ANTIBACTERIAL AGENTS AGAINST MDR BACTERIA
Suman Lata, Kavitha Kumari, Jasbir Sangwan, Vijay Kiran
Page No. : 190-201
ABSTRACT
The current study aims to explore a novel and cost-effective nano-therapeutic strategy for addressing Acinetobacter baumannii, Staphylococcus aureus, and Enterococci. This study presents a sustainable method for the swift production of silver nanoparticles (Ag-NPs) using an aqueous leaf extract derived from Corchorus Capsularis (CRCP). The production of stable silver nanoparticles (Ag-NPs) at various time intervals predominantly yields spherical particles with sizes ranging from 12 to 60 nm. The produced Ag-NPs were characterized using a variety of methods, TEM, FTIR, and UV-visible spectroscopy. According to the results of extensive investigation, it has been found that Ag-NPs are produced, with an average size of 22.32 nm. The goal of the study was to evaluate the antibacterial effectiveness of the created silver nanoparticles (Ag-NPs) against MDR strains of Acinetobacter baumannii, staphylococcus aureus, and enterococci that were isolated from infections in post-surgical wounds. The current investigation proposes that silver nanoparticles (Ag-NPs) produced using a water-based leaf extract of CRCP exhibit noteworthy antibacterial properties against multi-drug resistant (MDR) strains.
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