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A STUDY OF POLYCLONAL ANTIBODIES THAT ARE SPECIFIC TO PLASMODIUM LACTATE DEHYDROGENASE ARE KNOWN AS ANTI-IDIOTYPIC ANTIBODIES

Dr. Vivek Kumar Singh
Page No. : 168-173

ABSTRACT

Malaria is one of the primary parasite infections that pose a health risk to millions of individuals in impoverished countries, Despite enormous international efforts to eliminate malaria, the illness still poses a serious threat to global health, with an estimated 2 billion people at risk. There may be 300–500 million clinical cases of malaria worldwide each year (WHO, 1993), which results in 1,5-2,5 million deaths yearly, mostly affecting children under the age of 5 (Anonymous, 1996; WHO, 1997). Tropical Africa is home to about 85% of cases and 90% of carriers (many of whom are asymptomatic), yet in other nations the illness is responsible for 20–30% of paediatric deaths (Defo, 1995; WHO, 1996). Plasmodium vivax, Plasmodium malariae, Plasmodium falciparum, and Plasmodium ovale are the four species of protozoa that cause human malaria (Grassi and Feletti, 1892; Welch, 1897). Each Plasmodium species exhibits unique morphological traits in the blood smear that are connected to particular diseases.


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